cCeLL Ex-vivo
Surgical Instruments
Information
cCeLL Ex-vivo is a multi-fluorescence confocal endomicroscopic system for realtime, intraoperative digital biopsies during brain tumor surgery. cCeLL Ex-vivo consists
of a few main components: the cCeLL Main Unit, a miniaturized laser scanning device called “Pixection”, a computer, and an Auto-Stage for ex-vivo Pixection movement.
Upon contacting Pixection to resected tumor tissue, surgeons will be able to conduct non-invasive fluorescence imaging for real-time visualization of tissue microstructures. Pixection creates a Lissajous scanning pattern that can be generated via two different waveforms with different frequencies. These waveforms correspond to two FDA-approved fluorescence dyes, sodium fluorescein (FNa) and indocyanine green (ICG), demonstrating that cCeLL Ex-vivo’s technology is capable of detecting both of these dyes. Resulting from the Lissajous scanning pattern, surgeons can utilize cCeLL ex-vivo to
perform unlimited rapid high-resolution intraoperative imaging and digitally transfer images to pathologists for remote consultation.