Luxfill Plus (CE HA Filler)

Luxfill Plus is a Hyaluronic acid (HA) fi ller that has been recognized for its technology and safety through obtaining the CE certifi cation. This product is a bio-material for tissue restoration. A syringe is filled with 0.3% lidocaine hydrochloride with a derivative of cross-linked sodium hyaluronate originated from bacterial fermentation gel. It is intended to be used for facial tissue augmentation for mid-to-deep dermal implantation for the correction of moderate to severe facial wrinkles and nasolabial folds. The addition of lidocaine provides a pain-relieving effect during treatment Luxfill Plus is safe by integrating chemical and physical crosslinking and has high viscoelasticity and cohesion. Cross-linking, referring to the binding hyaluronic acid, is done by using BDDE, the most commonly employed cross- linking agent. Luxfi ll Plus can be used safely by minimizing the amount of BDDE input (about 60% of BDDE used for popular fillers), and minimizing impurities such as BDDE residues that are not completely crosslinked through a strict purifi cation process. It also uses ingredients listed in the European Directorate for the Quality of Medicines & Healthcare (EDQM) including hyaluronic acid, lidocaine, and BDDE to ensure safety. In addition, it applies physical crosslinking performed by the High-Density Tapping Process (h-DTP), a manufacturing system unique to the company, for which a patent has been applied. The h-DTP maintains the high viscoelasticity of the HA filler despite the use of a small amount of crosslinking agent, helping to extend the duration after the procedure.